Clonidine helps with high blood pressure

Clonidine helps with high blood pressure

The active ingredient clonidine is used to treat high blood pressure  . In addition, the drug is also used to reduce withdrawal symptoms in alcohol, drug or medication addiction. Ingestion can lead to numerous side effects – including fatigue, dry mouth and headaches. We will inform you in detail about the effects, side effects and dosage of clonidine.

effect of clonidine

Clonidine is primarily used in the  treatment of high blood pressure  (hypertension). The active ingredient ensures that less  adrenaline  and noradrenaline are released in the body. These two messenger substances ensure that the blood pressure is driven up. If your concentration drops, the blood vessels relax and widen and the heart has to work less hard. All of this also causes blood pressure to drop.

In addition to high blood pressure, clonidine can also be used as a support during anesthesia and to  combat withdrawal symptoms  . For example, the active ingredient helps to reduce withdrawal symptoms after addiction to alcohol, drugs or opioids.

side effect of clonidine

A number of side effects can occur while taking clonidine. The most common side effects include fatigue, drowsiness, and dry mouth. Headaches,  constipation , nausea and vomiting, erectile dysfunction and a slow heartbeat can also be noticeable. Occasionally, skin reactions and  itching  may also occur.

On the other hand, side effects such as dizziness, sleep disordersdepression , mood swings, sensory disturbances, confusion and hallucinations are rather rare  . Weight gain due to water retention is also rare.

To avoid further side effects, clonidine should never  be discontinued abruptly, but slowly and step by step  . Otherwise the so-called  rebound phenomenon  can occur. This can lead to an excessive counter-reaction from clonidine, which can lead to a very rapid and severe rise in blood pressure.

Clonidine dosage

Clonidine can be taken orally as a capsule or tablet, or injected intravenously, intramuscularly, or subcutaneously. In addition, the active ingredient is available in different doses. In general, you should always start with the lowest possible dose and then slowly increase it if necessary.

Unless otherwise recommended by the doctor, treatment is started with a dose of 0.075 milligrams. If necessary, the dose can then be further increased. However, the dosage should only be adjusted after about two to four weeks.

Contraindications: when not to take clonidine?

There are certain circumstances in which you must not take clonidine. This is especially the case if you are allergic to the active ingredient. In addition, clonidine is also contraindicated in the following diseases, or the patient requires careful medical supervision:

  • depressions
  • Low blood pressure
  • renal dysfunction
  • Cardiac arrhythmia  (AV block)
  • Fresh  heart attack
  • Bradycardia less than 50 beats per minute
  • polyneuropathy
  • Severe circulatory disorders
  • Severe coronary artery disease
  • constipation

The active substance must not be taken during pregnancy and lactation. Children should not be treated with clonidine either.

Clonidine: Interactions

If clonidine is taken at the same time as other medications, interactions may occur under certain circumstances. Therefore, always inform your treating doctor about which medications you take regularly.

Among other things, interactions with the following drugs are known:

  • Diuretics
  • Hypnotics
  • neuroleptics
  • Tricyclic antidepressants
  • Vasodilatantien

In addition, the intake of medications such as beta blockers, which also have an effect on blood pressure, should be avoided. Otherwise, cardiac arrhythmias and a slowing of the heartbeat may occur. Also make sure not to consume alcohol at the same time as the active ingredient, as this can increase the effect of clonidine.

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