COVID-19: These organs are particularly affected

While  COVID-19  was mostly referred to as a lung disease at the beginning of the pandemic, experts now classify the disease as a multi-organ disease. COVID-19 can be asymptomatic as well as mild to very severe. In the case of severe diseases, there are other complications in addition to pulmonary complaints. These can affect the gastrointestinal system, the heart and other parts of the body. You can find out here which organs are particularly affected in the event of a severe course and how this manifests itself.

1. Lung severely affected in COVID-19

If the virus travels from the throat to the lower airways, the virus begins to multiply in the lungs, which can lead to serious respiratory system disease.

In the early stages of the disease, different parts of the lungs, including the lung parenchyma, suffer from the infection. This is the part of the lungs in which the actual breathing process takes place, as this is where the gas exchange of the alveoli takes place. Inflammatory fluid deposits also form.

The structure of the lungs hardens, which can lead to an increase in the radiologically measured lung weight and indicates damage to the lungs. Bacterial infections cannot be ruled out in this context either.

Lying on your stomach can help decongest your lungs and make breathing easier. In the case of severe lung complications, those affected must be artificially ventilated and, in the worst case, connected to an ECMO device.

2. Hyperinflammation: An overreaction of the immune system

The  immune system  begins to defend itself and reacts with various mechanisms. Among other things, it produces cytokines, which control the growth of the cells and distinguish them from one another.

However, in some of those affected, the immune system overreacts – the result: an uncontrolled release of cytokines, also known as cytokine storm, which can lead to a strong inflammatory reaction and even to multi-organ failure.

The blood vessels in particular are affected, which in turn has a negative effect on the heart, kidneys and intestines. The structure of the lungs can also change as a result, increasing the risk of  thrombosis  and embolism.

3. Kidneys suffer from COVID-19

Experts assume that the virus can get directly into the blood via the damaged lungs and thus also affect the kidneys.

Acute kidney damage occurs, which can range from non-specific kidney congestion, in which urine can no longer be excreted, to damage to cell functions. A heavy load on the right side of the heart is also possible due to kidney damage.

According to calculations, around 50 percent of those affected suffer from kidney problems, which can also increase the risk of death.

4. Heart: cardiac disorders in COVID-19

Infected people with previous cardiac diseases are particularly at risk of a severe course and increased mortality. Common heart conditions described during COVID-19 illness are:

Even with a mild corona course, heart muscle inflammation is possible, for example. Medical advice should therefore be sought for symptoms such as tightness, chest pain, tiredness and dizziness.

5. COVID-19 effects on the gut

The gastrointestinal system can also be affected by SARS-CoV-2. Common symptoms are severe  diarrhea  and acute mesenteric ischemia. The blood flow in the gastrointestinal tract is blocked by thrombosis and embolism, inflammatory reactions, septic shock or multi-organ failure occur.

6. Influence on the nervous system

The nervous system is affected in mild and severe corona courses. Common complaints are:

  • headache
  • fatigue
  • exhaustion
  • Disorders of smell and  taste
  • inflammation of the brain

The symptoms can occur during the illness, but are also known as long-COVID symptoms. Memory loss or word finding difficulties can also occur.

In order to prevent a severe corona course and long-term consequences, experts continue to recommend basic immunization and a booster vaccination.

 

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